肺の新血管性:アイゼンメンガー症候群の特徴的な放射線検査結果
Ramon Sheehan1, Joseph K Perloff, Michael C Fishbein
1Division of Thoracic Imaging, Department of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-1721, USA.
Circulation
|November 4, 2005
まとめ
アイゼンメンゲル症候群はイメージングでユニークな肺血管異常を示します. これらの発見は,特定の組織学的病変,特にトリコスピッド後伝達と相関しています.
科学分野:
- 心臓病学 心臓病学
- 放射線学 放射線学
- 肺内科 肺内科 肺内科
背景:
- アイゼンメンゲル症候群は,肺血管の複雑な異常を伴う.
- これらの異常をイメージングで特徴づけることは,診断と管理に不可欠です.
研究 の 目的:
- 胸部X線写真とCTスキャンを使用して,アイゼンメンガー症候群の特徴的な肺血管異常を特徴付ける.
- 画像検査の発見をヒト病理学的特徴と臨床データと相関させる.
主な方法:
- 胸部CTスキャン,胸部X線写真,24人のアイゼンメンガー症候群患者と14人のアシアノティック肺動脈高血圧 (PAH) 患者からの臨床データのレビュー.
- 2人の胸部放射線科医による新血管性,グラウンドガラスの不透明化,および全身的付随のCTスキャンの盲検スコア付け.
- アイゼンメンガー症候群と亜陽性PAH患者からの肺部セクションのヒト内病理学的レビュー.
主要な成果:
- CTスキャンでは,アシアノティックPAHと比較して,アイゼンメンガー症候群では,新血管性,グラウンドガラスの不透明化,および全身的な副作用の有病率と重症度がより高いことが明らかになりました.
- これらの異常は,トリコスピッド後のコミュニケーションを持つ患者でより顕著でした.
- アイゼンメンゲル症候群では3つの新しい血管病変が組織学的に特定されました.
結論:
- アイゼンメンガー症候群における胸部X線写真とCTスキャンで観察された特徴的な血管病変は,特定の組織学的発見と関連しています.
- 付近血管の範囲は,心臓の伝達の種類と相関しており,三骨後ではより広範囲である.
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