関連する実験動画
Updated: May 12, 2026

12:50
Using Whole Mount in situ Hybridization to Link Molecular and Organismal Biology
Published on: March 31, 2011
ホックス遺伝子:モータープールで働くインストラクター
Mi-Ryoung Song1, Samuel L Pfaff
1Gene Expression Laboratory, The Salk Institute, La Jolla, California 92037, USA.
Cell
|November 5, 2005
まとめ
ホックス遺伝子は,脊髄のモータープール開発を指示する. この研究は,どのようにモーターニューロンが正確な筋肉内置のためにユニークなアイデンティティを獲得するのかを明らかにしています.
科学分野:
- 神経科学は神経科学である.
- 発達生物学 発達生物学について
- 遺伝学 遺伝学とは
背景:
- モーターニューロンは,正確な軸索誘導と筋肉内置のために特定のアイデンティティを必要とします.
- モーターニューロン細胞体は,脊髄のモータープールと呼ばれる明確なグループを形成します.
- モーターニューロン多様化の基礎となる分子メカニズムは,ほとんど未知のままでした.
関連する概念動画
Motor Units
A motor unit consists of two main components: a single efferent motor neuron (i.e., a neuron that carries impulses away from the central nervous system) and all of the muscle fibers it innervates. The motor neuron may innervate multiple muscle fibers, which are single cells, but only one motor neuron innervates a single muscle fiber.
Combinatorial Gene Control
Combinatorial gene control is the synergistic action of several transcriptional factors to regulate the expression of a single gene. The absence of one or more of these factors may lead to a significant difference in the level of gene expression or repression.
The expression of more than 30,000 genes is controlled by approximately 2000-3000 transcription factors. This is possible because a single transcription factor can recognize more than one regulatory sequence. The specificity in gene...
The expression of more than 30,000 genes is controlled by approximately 2000-3000 transcription factors. This is possible because a single transcription factor can recognize more than one regulatory sequence. The specificity in gene...
Master Transcription Regulators
Master transcription regulators are regulatory proteins that are predominantly responsible for regulating the expression of multiple genes. Often these genes work in concert to drive a complex process. Activation of a master transcription regulator can lead to a cascade of transcriptional activation necessary for that outcome. These regulators can directly bind to the regulatory sequences of the various genes involved, or they can indirectly regulate transcription by binding to regulatory...
Master Transcription Regulators
Master transcription regulators are regulatory proteins that are predominantly responsible for regulating the expression of multiple genes. Often these genes work in concert to drive a complex process. Activation of a master transcription regulator can lead to a cascade of transcriptional activation necessary for that outcome. These regulators can directly bind to the regulatory sequences of the various genes involved, or they can indirectly regulate transcription by binding to regulatory...
Motor Units
The motor unit is a fundamental component of the neuromuscular system and plays a crucial role in coordinating muscle contractions. It consists of a somatic motor neuron, which connects and controls multiple skeletal muscle fibers, forming a single functional segment. The axon of the motor neuron branches out and establishes synaptic connections known as neuromuscular junctions with individual muscle fibers within the motor unit.
Motor units come in different sizes, with smaller units...
Motor units come in different sizes, with smaller units...
Hierarchy of Motor Control
The hierarchy of motor control refers to the different levels of organization and processing involved in controlling movement in the body. These levels range from higher cortical areas involved in planning and decision-making to lower spinal cord reflexes that respond automatically to external stimuli.

