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Updated: Apr 11, 2026

Extracellularly Identifying Motor Neurons for a Muscle Motor Pool in Aplysia californica
13:37

Extracellularly Identifying Motor Neurons for a Muscle Motor Pool in Aplysia californica

Published on: March 25, 2013

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A Hox 規制ネットワークは,モーターニューロンプールアイデンティティとターゲット筋肉の接続性を確立します

Jeremy S Dasen1, Bonnie C Tice, Susan Brenner-Morton

  • 1Howard Hughes Medical Institute, Department of Biochemistry and Molecular Biophysics, NY 10032, USA.

Cell
|November 5, 2005
PubMed
まとめ

ホックス転写制御ネットワークは,脊髄運動ニューロンプールアイデンティティと筋肉の接続性を決定する. このネットワークは,神経細胞の特異性にとって極めて重要な rostrocaudal ポジショニングとセグメンタル多様性を確立します.

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Motor Units00:46

Motor Units

A motor unit consists of two main components: a single efferent motor neuron (i.e., a neuron that carries impulses away from the central nervous system) and all of the muscle fibers it innervates. The motor neuron may innervate multiple muscle fibers, which are single cells, but only one motor neuron innervates a single muscle fiber.
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Master transcription regulators are regulatory proteins that are predominantly responsible for regulating the expression of multiple genes. Often these genes work in concert to drive a  complex process. Activation of a master transcription regulator can lead to a cascade of transcriptional activation necessary for that outcome. These regulators can directly bind to the regulatory sequences of the various genes involved, or they can indirectly regulate transcription by binding to regulatory...
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Formation of Muscle Fibers from Myoblasts

De novo myogenesis, or the formation of muscle fibers, begins during the early embryonic stages. The skeletal muscle is formed from somites– blocks of embryonic cell layers. The somites are further divided into dermatomes, myotomes, sclerotomes, and syndetomes. Among these, the myotomes give rise to muscle fibers.
Muscle progenitor cells (MPCs) are formed from the myotomes. MPCs express genes that encode the transcription factors Pax3 and Pax7. Along with Pax 3/7, other transcription...
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The nervous system consists of complex motor neuron circuits, including upper motor neurons originating from the cerebral cortex and lower motor neurons starting in the spinal cord, coordinating both voluntary and involuntary movements. Among these, somatic motor neurons activate skeletal muscles and are classified into alpha, beta, and gamma types. Alpha neurons are vital for voluntary movement coordination, while gamma neurons adjust muscle spindle sensitivity, and the function of beta...
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Motor Units01:13

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The motor unit is a fundamental component of the neuromuscular system and plays a crucial role in coordinating muscle contractions. It consists of a somatic motor neuron, which connects and controls multiple skeletal muscle fibers, forming a single functional segment. The axon of the motor neuron branches out and establishes synaptic connections known as neuromuscular junctions with individual muscle fibers within the motor unit.
Motor units come in different sizes, with smaller units...
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The hierarchy of motor control refers to the different levels of organization and processing involved in controlling movement in the body. These levels range from higher cortical areas involved in planning and decision-making to lower spinal cord reflexes that respond automatically to external stimuli.
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