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Updated: Jul 8, 2026

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組織特異のTAFは,ポリコンブに抵抗し,端末分化をオンにします

Xin Chen1, Mark Hiller, Yasemin Sancak

  • 1Departments of Developmental Biology and Genetics, Stanford University School of Medicine, Stanford, CA 94305-5329, USA.

Science (New York, N.Y.)
|November 8, 2005
PubMed
まとめ

胞特異のTBP関連因子 (TAF) は,男性生殖細胞の微分化を可能にするためにポリコンブ抑制に対抗する. これらの精巣TAFはポリコンブ結合を減少させ,活性表遺伝子マークを促進し,細胞運命を変化させる.

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