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Updated: Jun 25, 2026

Determination of the Relative Potency of an Anti-TNF Monoclonal Antibody (mAb) by Neutralizing TNF Using an In Vitro Bioanalytical Method
16:07

Determination of the Relative Potency of an Anti-TNF Monoclonal Antibody (mAb) by Neutralizing TNF Using an In Vitro Bioanalytical Method

Published on: September 16, 2017

小分子抑制によるTNF-αの抑制

Molly M He1, Annemarie Stroustrup Smith, Johan D Oslob

  • 1Sunesis Pharmaceuticals, Incorporated, 341 Oyster Point Boulevard, South San Francisco, CA 94080, USA.

Science (New York, N.Y.)
|November 15, 2005
PubMed
まとめ

新しい小分子阻害剤は,そのサブユニット解離を促進することによって,腫瘍死滅因子α (TNF-α) を破壊する. この化合物は,TNF-αの活性を効果的に抑制し,新しい治療法を提供しています.

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