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Updated: Jul 6, 2026

Yeast As a Chassis for Developing Functional Assays to Study Human P53
14:57

Yeast As a Chassis for Developing Functional Assays to Study Human P53

Published on: August 4, 2019

スラッグアウト:p53-PUMA死の接続の微調整

Jack T Zilfou1, Mona S Spector, Scott W Lowe

  • 1Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, New York 11724, USA.

Cell
|November 16, 2005
PubMed
まとめ

腫瘍抑制剤p53がSLUGを誘発し,血球原始細胞をDNA損傷誘発のアポトーシスから保護し,プロアポトーシス因子PUMAを抑制する. これは,DNAの損傷に対する新しい保護機構を明らかにします.

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