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Updated: May 12, 2026

Polysome Fractionation and Analysis of Mammalian Translatomes on a Genome-wide Scale
10:56

Polysome Fractionation and Analysis of Mammalian Translatomes on a Genome-wide Scale

Published on: May 17, 2014

mTORとS6K1は,ダイナミックなタンパク質交換とオーダーされたリン酸化イベントを通じた翻訳前始動複合体の中間組成を介しています

Marina K Holz1, Bryan A Ballif, Steven P Gygi

  • 1Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA.

Cell
|November 16, 2005
PubMed
まとめ

この研究では,真核の初期因子3 (eIF3) 複合体が,細胞信号への反応としてタンパク質合成を制御するために,S6キナーゼ1 (S6K1) のダイナミックな活性化をオーケストラ化して,支架としてどのように作用するかを明らかにしました.

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