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A Simplified Technique for Producing an Ischemic Wound Model
Published on: May 2, 2012
糖尿病の足の潰瘍の治療法
Peter R Cavanagh1, Benjamin A Lipsky, Andrew W Bradbury
1Diabetic Foot Care Program, Department of Biomedical Engineering, and the Orthopaedic Research Center, Cleveland Clinic Foundation, Cleveland 44195, OH, USA. cavanap@ccf.org
Lancet (London, England)
|November 18, 2005
まとめ
糖尿病の足の潰瘍は,神経病とイシュケミアに起因し,しばしば感染症によって悪化します. 効果的な治療には,減圧 (オフロード),適切な抗菌剤療法,再発を防ぐための患者教育が含まれます.
科学分野:
- ポディアトリー ( Podiatry) とは
- 糖尿病学 糖尿病学
- 血管外科 血管外科
背景:
- 糖尿病の足の潰瘍は,神経病,イシュケミア,またはその両方から生じ,トラウマまたは機械的ストレスによって開始されます.
- 感染症は糖尿病の足の潰瘍を肢体または生命を脅かすものにして,迅速な診断と治療を必要とします.
- 効果的な管理には,感染制御と並行して,神経病変や缺血などの根本的な原因に対処することが必要です.
研究 の 目的:
- 糖尿病の足の潰瘍の原因と病理生理学の概要を述べる.
- 感染症と缺血の診断方法について説明する.
- オフロード,抗菌剤療法,外科的介入,再発防止を含む治療戦略を詳細に説明する.
主な方法:
- 神経病,性缺血,感染症の臨床評価について.
- 肢体イシュケミアのための血管外科のコンサルティング.
- 病原体識別のための傷口培養 (組織サンプルが望ましい).
- 培養結果による抗菌剤療法.
- トータルコンタクト鋳造を含む機械的な脱荷戦略.
- 潰瘍の治癒と再発の予防のための外科的介入.
- 患者の教育と治癒後の靴の提供.
主要な成果:
- 神経病性潰瘍は,効果的な減圧と遵守により,完全なコンタクト鋳造で6週間以内に治癒することができます.
- 抗菌薬療法は,傷の治癒ではなく,培養結果に基づいて感染を標的とするべきである.
- 手術は潰瘍を治すことができるが,合併症や二次潰瘍のリスクを伴う.
- 高い潰瘍再発率は,患者教育,専門の靴,定期的な足のケアを通じて減らすことができます.
結論:
- 糖尿病の足の潰瘍の管理には,神経病,性欠血症,感染症,および機械的ストレスに対処する多分野的なアプローチが必要です.
- 脱荷は治癒に不可欠であり,神経病性潰瘍ではトータルコンタクト・キャスティングが非常に効果的です.
- 患者の教育,適切な靴,および再発を最小限に抑えるために継続的な足のケアを強調して,再発を予防することが重要です.
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