関連する実験動画

Updated: Jun 19, 2026

Quantification of γH2AX Foci in Response to Ionising Radiation
06:53

Quantification of γH2AX Foci in Response to Ionising Radiation

Published on: April 7, 2010

ガンマH2AXを脱リン酸化するフォスファターゼ複合体は,DNA損傷の回復チェックポイントを調節します

Michael-Christopher Keogh1, Jung-Ae Kim, Michael Downey

  • 1Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA.

Nature
|November 22, 2005
PubMed
まとめ

Pph3を含む新しいヒストンH2Aフォスファタゼ複合体 (HTP-C) は,DNA二重鎖断裂 (DSB) の重要なマーカーであるgammaH2AXを効率的に分解する. この脱リン酸化は,DNA損傷のチェックポイントからタイムリーに回復するために不可欠です.

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