授乳期間と2型糖尿病の発生率

Alison M Stuebe¹, Janet W Rich-Edwards, Walter C Willett

¹Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women's Hospital, and Harvard Medical School, Boston, Mass 02115, USA.

JAMA

|November 24, 2005

まとめ

乳児の授乳期間が長くなると,女性における2型糖尿病のリスクが著しく低下する. この発見は,代謝の健康と病気の予防のための母乳育児の利点を強調しています.

科学分野:

生殖器保健は,生殖器の健康についてです.
エンドクリノロジーエンドクリノロジー
エピデミオロジーエピデミオロジー

背景:

哺乳期は体重に関係なく,グルコースとインスリン調節に好影響を与える.
哺乳期が代謝健康に及ぼす長期的な影響を理解することは極めて重要です.

研究の目的:

授乳歴と2型糖尿病の発生率との関連を調査する.
授乳期間が長くなる2型糖尿病のリスク低下を定量化するために.

主な方法:

看護師の健康研究 (NHS) に参加した83,585人の女性を対象とした前向きな観察コホート研究.
看護師の健康研究II (NHS II) に参加した73,418人の女性を対象とした遡及的観察コホート研究.
分析は,延長されたフォローアップ期間中に発生した2型糖尿病の症例に焦点を当てた.

主要な成果:

哺乳期間の延長は,2型糖尿病を発症するリスクの低下と相関する.
授乳期間が1年増えると,前15年間に出産した女性の糖尿病リスクが14~15%低下することがわかりました.
これらの関連性は,ボディマス指数および他の糖尿病リスク要因をコントロールした後も依然として有意であった.

結論:

延長された授乳期間は,米国の大規模なコホートにおける2型糖尿病の発生率の低下と関連しています.
授乳は,グルコースホメオスタシスを強化することによって,女性における2型糖尿病に対する保護を提供することができる.

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