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Updated: Jul 6, 2026

Combining Wet and Dry Lab Techniques to Guide the Crystallization of Large Coiled-coil Containing Proteins
11:14

Combining Wet and Dry Lab Techniques to Guide the Crystallization of Large Coiled-coil Containing Proteins

Published on: January 6, 2017

成長因子-β2の結晶構造:超家族にとって珍しい折りたたみ

S Daopin1, K A Piez, Y Ogawa

  • 1Laboratory of Molecular Biology, National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892.

Science (New York, N.Y.)
|July 17, 1992
PubMed
まとめ

トランスフォーミング成長因子β2 (TGFβ2) の結晶構造は,二酸化硫化物結合と防水相互作用によって安定した長方形の折り目を明らかにしています. この構造は,他のTGF-βスーパーファミリーのメンバーが同様の折り畳みを共有することを示唆しており,これは細胞の調節に不可欠です.

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