末動脈疾患のある患者およびない患者における運動による足の痛み
Jimmy C Wang1, Michael H Criqui, Julie O Denenberg
1University of California, School of Medicine, San Diego, CA, USA.
Circulation
|December 1, 2005
まとめ
運動による足の痛みの症状は様々であり,単一の痛みのタイプでは,周辺動脈疾患 (PAD) を確実に診断することはできません. 正常な足首-腕指数 (ABI) は1.00から1.39の範囲で,他の要因も足の痛みと相関しています.
科学分野:
- 血管医学 血管医学とは
- 診断の精度 診断の精度
- エピデミオロジー エピデミオロジー
背景:
- 運動による足の痛みは,周辺動脈疾患 (PAD) の主要な症状です.
- 運動による足の痛みにおける症状の変動はよく理解されていません.
- PADは人口のかなりの部分に影響します.
研究 の 目的:
- 運動による足の痛みの特徴と周辺動脈疾患 (PAD) の間の関係を調査する.
- PADの異なる脚の痛みカテゴリーの診断的有用性を決定する.
- PAD診断を超えて,運動による足の痛みに関連する要因を特定するために.
主な方法:
- 横断分析のための3つのコホート研究からのデータを組み合わせた.
- サンディエゴのクラウディケーションアンケートを使用して,運動による足の痛みを評価しました.
- 足首-腕指数 (ABI) <または=0.90を使用したPADの定義または下肢再血管化の歴史.
主要な成果:
- 分析された被験者の24.1%がPADを持っていた.
- 痛みを感じない状態からクラシックなクラウジケーションまで,痛みのカテゴリー全体で平均ABIの段階的な低下が観察されました.
- 低正常 (0.91-0.99) と高正常 (>=1.40) ABIsを持つ足では,痛みの割合が増加し,境界性疾患と血管の硬さを示唆しました.
- ABIは,その範囲全体で痛みのカテゴリと強く相関していました.
- 年齢,男性性別,糖尿病,喫煙,高BMI,心筋梗塞,および以前の再血管化は,足の痛みの独立した相関値でした.
結論:
- 運動による足の痛みのカテゴリーは,通常のPAD診断に十分敏感または特異的ではありません.
- 通常のABIは,おそらく1.00から1.39の範囲です.
- ABIに加えて,いくつかの危険因子は,運動による足の痛みと独立して相関しています.
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