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Updated: Apr 10, 2026

Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes
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Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes

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TWEAKは,先天性免疫から適応性免疫への移行を弱める

Heather Maecker1, Eugene Varfolomeev, Frank Kischkel

  • 1Department of Molecular Oncology, Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, USA.

Cell
|December 6, 2005
PubMed
まとめ

腫瘍死滅因子のような弱い誘発性アポトーシス (TWEAK) タンパク質は,先天的免疫を抑制し,自然殺菌 (NK) 細胞の活動とインターフェロン-ガンマ (IFN-γ) 生産を減少させます. このTWEAK機能は,適応性Tヘルパー1 (TH1) 免疫応答への移行を制限する.

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