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Updated: May 6, 2026

Chemotherapy-induced Vascular Toxicity - Real-time In vivo Imaging of Vessel Impairment
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NAD(P) H酸化酵素と多剤耐性タンパク質の遺伝的多形態化は,ドクソルビシン誘発の心臓毒性に関連しています

Leszek Wojnowski1, Bettina Kulle, Markus Schirmer

  • 1Department of Pharmacology, University Mainz, D-55101 Mainz, Germany. Wojnowski@uni-mainz.de

Circulation
|December 7, 2005
PubMed
まとめ

薬物の輸送と代謝における遺伝的変異は,アントラサイクリン誘発性心臓毒性 (ACT) リスクに影響します. これらの薬剤ゲノミクス予測因子を特定することで,がん治療をパーソナライズし,心臓の損傷を軽減するのに役立ちます.

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