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Updated: Jul 14, 2026

Wild-type Blocking PCR Combined with Direct Sequencing as a Highly Sensitive Method for Detection of Low-Frequency Somatic Mutations
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Published on: March 29, 2017

uracil-directed ligand tethering: uracil DNA glycosylase (UNG) 阻害剤の開発のための効率的な戦略

Yu Lin Jiang1, Daniel J Krosky, Lauren Seiple

  • 1Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, Maryland 21205, USA.

Journal of the American Chemical Society
|December 8, 2005
PubMed
まとめ

研究者らは, uracil DNA glycosylase (UNG) の阻害剤を見つけるための新しい uracil-directed ligand tethering 戦略を開発しました. この方法は,酵素を標的とする新しい小分子阻害剤を迅速に特定しました.

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