蛇のPLA2神経毒とリソホスフォリピドと脂肪酸の混合物の等価な効果

Michela Rigoni1, Paola Caccin, Steve Gschmeissner

  • 1Department of Biomedical Sciences and Consiglio Nazionale Ricerche Institute of Neuroscience, University of Padova, Italy.

Science (New York, N.Y.)
|December 13, 2005
PubMed
まとめ

蛇の神経毒素 (SPAN) は,シナプス腫れと神経伝達物質の放出を引き起こし,神経筋肉の結節を麻痺させます. リソホスフォリピドと脂肪酸は,これらの効果を模倣し,シナプス水泡の放出における局所性脂質変化の役割を示唆しています.

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