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Updated: Jul 15, 2026

Detection and Visualization of DNA Damage-induced Protein Complexes in Suspension Cell Cultures Using the Proximity Ligation Assay
13:10

Detection and Visualization of DNA Damage-induced Protein Complexes in Suspension Cell Cultures Using the Proximity Ligation Assay

Published on: June 9, 2017

PIDDは,DNA損傷に対する反応としてNF-kappaBの活性化を媒介する

Sophie Janssens1, Antoine Tinel, Saskia Lippens

  • 1Department of Biochemistry, University of Lausanne, BIL Biomedical Research Center, Chemin des Boveresses 155, CH-1066 Epalinges, Switzerland.

Cell
|December 20, 2005
PubMed
まとめ

タンパク質PIDDは,DNA損傷後のNF-kappaBシグナリングを活性化して,細胞生存と化学抵抗を促進するために不可欠です. この発見は,がん治療の改善を目的にできる経路に光を当てています.

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