突然の乳児死亡症候群および他の妊娠における合併症
Gordon C S Smith1, Angela M Wood, Jill P Pell
1Department of Obstetrics and Gynaecology, Cambridge University, Rosie Hospital, Cambridge CB2 2SW, UK. gcss2@cam.ac.uk
Lancet (London, England)
|December 20, 2005
まとめ
突然の乳児死亡症候群 (SIDS) を経験している女性は,妊娠合併症を持つ可能性が高くなります. 繰り返される妊娠問題は,次の出産でSIDSの繰り返し発生に寄与する可能性があります.
科学分野:
- 産婦人科と産婦人科を担当しています.
- 新生児の健康について
- エピデミオロジー エピデミオロジー
背景:
- 突然の幼児死亡症候群 (SIDS) の再発は,生物学的,臨床的,法的意味合いを持つ重要な懸念事項です.
- 産科合併症は,SIDSのリスクの増加と関連しており,次の妊娠で再発する傾向があります.
- この研究では,以前のSIDSと他の妊娠における産科合併症の関連性を調査しました.
研究 の 目的:
- SIDSで乳児が死亡した女性が,他の妊娠で産科合併症を経験する可能性が高いかどうかを判断する.
- SIDSに誘導する可能性がある妊娠合併症の再発パターンを調査する.
主な方法:
- リンクされた英国の国家データベースを利用した:産婦人病院退院,胎児死亡,死亡証明書.
- 1985年から2001年の間にスコットランドで連続出産した258,096人の女性のデータを分析した.
- SIDS,産科合併症,再発との関連を特定し説明するために多変量分析を使用しました.
主要な成果:
- 以前のSIDSの乳児を持つ女性は,次の妊娠では,妊娠年齢に対して小さい (OR 2.27) と早産児 (OR 2.53) を出産するリスクが高くなります.
- 妊娠年齢に対して小さい (OR 1.87) または早産児 (OR 1.93) の母親から生まれた子供は,SIDSのリスクが高くなりました.
- 多変量分析は,一般的な母性リスク因子と胎児の成長制限と早産の再発がこれらの関連性を説明することを示しました.
結論:
- 乳児がSIDSに罹患した女性は,他の妊娠で合併症に罹患する可能性が統計的に高い.
- SIDSを誘発する妊娠合併症の再発は,一部の家族におけるSIDSの再発症例を部分的に説明する可能性があります.
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