関連する実験動画
Updated: May 6, 2026

05:12
Pressure-polishing Pipettes for Improved Patch-clamp Recording
Published on: October 22, 2008
12.3K
ピンで乒乓球をする:皮質と微小管によって引き起こされる極性
1The Gurdon Institute and Department of Genetics, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, United Kingdom. jaa@mole.bio.cam.ac.uk
Cell
|December 27, 2005
まとめ
細胞の極性は,典型的にはミトスのスパインドルを指向する. この研究では,ドロソフィラのニューロブラストでは,スパインドルは皮質細胞の極性にも影響を及ぼし,細胞分裂における新しいフィードバックメカニズムを示しています.
科学分野:
- 細胞生物学 細胞生物学
- 発達生物学 発達生物学とは
- 遺伝学 遺伝学とは
背景:
- 皮質細胞の極性は,様々な細胞タイプにおけるミトーシス・スパインドルの方向性を指向するために重要である.
- 確立されたモデルは,極性情報が皮質からスパインドルに一方的に流れることを示唆しています.
研究 の 目的:
- 皮質の極性とミトスのスパインドルの方向性との相互関係を調査する.
- スピンドルそのものが皮質の極性に影響を与えるかどうかを判断する.
主な方法:
- ドロソフィラのニューロブラストをモデルシステムとして利用した.
- 先進的な顕微鏡技術と遺伝子操作技術を用いて,細胞の極性やスパインドルダイナミクスを観察し,混乱させました.
主要な成果:
- ミトス・スピンドルが極化活性を持つことを実証した.
- スピンドルが皮質における極性因子の分布に積極的に影響することを示した.
- 皮質とスパインドル間の極性情報の非一方的な転送が確認されました.
結論:
- 細胞の極性を確立する際の皮質とミトシスピンドルの相互作用は,双方向的である.
- この相互調節は,細胞分裂と発達において重要な役割を果たします.
関連する概念動画
Pinocytosis
62.8K
Cells use energy-requiring bulk transport mechanisms to transfer large particles, or large amounts of small particles, into or out of the cell. The cells envelop the particles in spherical membranes called vesicles or vacuoles. Vesicles that transport material into the cell are built from the cell membrane. These vesicles encapsulate external molecules and transport them into the cell in a process called endocytosis.
62.8K
Mechanisms of Membrane-bending
2.6K
The living membranes are flexible due to their fluid mosaic nature; however, their bending into different shapes is an active process regulated by specific lipids and proteins. The membrane bending can be transient as seen in vesicles or stable for a long time as in microvilli. Cells regulate the size, location, and duration of the membrane curvature.
Membrane bending can happen due to intrinsic changes in lipid composition or extrinsic association with different proteins. The proteins involved...
Membrane bending can happen due to intrinsic changes in lipid composition or extrinsic association with different proteins. The proteins involved...
2.6K
Pinocytosis
4.0K
Cells use energy-requiring bulk transport mechanisms to transfer large particles or large numbers of small particles into or out of the cell. The cells envelop the particles in spherical membranes called vesicles or vacuoles. Vesicles that transport material into the cell are built from the cell membrane. These vesicles encapsulate external molecules and transport them into the cell in a process called endocytosis.
Pinocytosis ("cellular drinking") is one of three main types of...
Pinocytosis ("cellular drinking") is one of three main types of...
4.0K
Muscle Stimulation Frequency
4.7K
The contraction strength of muscles is regulated by motor neurons, which modulate the frequency of action potentials dispatched to the motor units based on the body's requirements. This process of varying the muscle stimulation frequency allows muscles to contract with a force that is precisely tailored to the needs of the moment, whether lifting a feather or a heavy box.
Wave summation
At low firing rates, motor neurons induce individual twitch contractions in muscle fibers. These twitches...
Wave summation
At low firing rates, motor neurons induce individual twitch contractions in muscle fibers. These twitches...
4.7K
Conservation of Linear Momentum for a System of Particles
717
In the dynamic realm of billiards, a fascinating interplay of forces governs the motion of cue balls and stationary balls. When the cue ball collides with a stationary ball, linear momentum is exchanged. The cue ball imparts a fraction of its linear momentum to the stationary ball, causing the cue ball to decelerate while initiating the motion of the stationary ball.
The impulsive force at play during this interaction is of extremely short duration, rendering its impulse negligible. When...
The impulsive force at play during this interaction is of extremely short duration, rendering its impulse negligible. When...
717
Poisson's Ratio
2.4K
Poisson's ratio is a material property that indicates their stress response. It explains the connection between the elongation or compression a material undergoes in the direction of an applied force and the contraction or expansion it experiences perpendicular to that force. When a slender bar is loaded axially, it stretches in the direction of the force and contracts laterally. Poisson's ratio is the negative ratio of this lateral contraction to the axial elongation. The negative sign...
2.4K

