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Updated: Jul 14, 2026

Fractionation for Resolution of Soluble and Insoluble Huntingtin Species
07:08

Fractionation for Resolution of Soluble and Insoluble Huntingtin Species

Published on: February 27, 2018

ハンティングチン媒介の転写抑制のインビトロ分析は,複数の転写因子標的を明らかにする

Weiguo Zhai1, Hyunkyung Jeong, Libin Cui

  • 1Department of Molecular and Cell Biology, Howard Hughes Medical Institute, University of California, Berkeley, 401 Barker Hall, Berkeley, CA 94720, USA.

Cell
|December 27, 2005
PubMed
まとめ

ハンチントン病は,転写に関する問題を伴う. 変異したハンティングチンタンパク質 (htt) は,転写因子とメカニズムを直接抑制し,RAP30は,この効果を相殺することによって神経保護を提供します.

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Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter11:32

Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter

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Efficient and Scalable Production of Full-length Human Huntingtin Variants in Mammalian Cells using a Transient Expression System10:52

Efficient and Scalable Production of Full-length Human Huntingtin Variants in Mammalian Cells using a Transient Expression System

Published on: December 10, 2021

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