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Updated: Jun 18, 2026

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation
08:43

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation

Published on: May 31, 2016

骨髄細胞におけるサイクロオキシゲネーゼ-1欠乏症は,アポリポプロテインEおよび低密度リポプロテイン受容体ゼロのマウスの早期動脈硬化症を増加させる

Vladimir R Babaev1, Lei Ding, Jeff Reese

  • 1Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. vladimir.babaev@vanderbilt.edu

Circulation
|December 29, 2005
PubMed
まとめ

骨髄細胞におけるサイクロオキシゲナーゼ-1 (COX-1) 欠乏は,マウスの動脈硬化症を悪化させる. これは,血小板トロンボキサン生成が早期の病変形成を促進せず,マクロファージにおけるCOX-2のアップレギュレーションがプロアテロゲンであることを示唆しています.

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