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関連する概念動画

What are Membranes?01:54

What are Membranes?

A key characteristic of life is the ability to separate the external environment from the internal space. To do this, cells have evolved semi-permeable membranes that regulate the passage of biological molecules. Additionally, the cell membrane defines a cell’s shape and interactions with the external environment. Eukaryotic cell membranes also serve to compartmentalize the internal space into organelles, including the endomembrane structures of the nucleus, endoplasmic reticulum and Golgi...
Membrane Fluidity01:23

Membrane Fluidity

Cell membranes are composed of phospholipids, proteins, and carbohydrates loosely attached to one another through chemical interactions. Molecules are generally able to move about in the plane of the membrane, giving the membrane its flexible nature called fluidity. Two other features of the membrane contribute to membrane fluidity: the chemical structure of the phospholipids and the presence of cholesterol in the membrane.Fatty acids tails of phospholipids can be either saturated or...
What are Membranes?01:24

What are Membranes?

A cell's plasma membrane demarcates the cell's borders and determines the nature of its interaction with the environment. Cells exclude certain substances, take in others, and excrete some others in controlled quantities. The plasma membrane must be flexible to allow certain cells, such as red and white blood cells, to change their shape while passing through narrow capillaries. These are the more obvious plasma membrane functions. In addition, the plasma membrane's surface carries markers that...
Membrane Fluidity01:26

Membrane Fluidity

Membrane fluidity is explained by the fluid mosaic model of the cell membrane, which describes the plasma membrane structure as a mosaic of components—including phospholipids, cholesterol, proteins, and carbohydrates—that gives the membrane a fluid character.
Mosaic nature of the membrane
The mosaic characteristic of the membrane helps the plasma membrane remain fluid. The integral proteins and lipids exist as separate but loosely-attached molecules in the membrane. The membrane is a relatively...
Tissue Membranes01:27

Tissue Membranes

A tissue membrane is a thin layer of cells that covers the outside of the body, the organs, internal passageways that lead to the exterior of the body, and the lining of the moveable joint cavities. There are two basic types of tissue membranes— connective tissue and epithelial membranes.
Connective Tissue Membranes
The connective tissue membrane is formed solely from connective tissue. These membranes encapsulate organs, such as the kidneys, and line our movable joints. A synovial membrane is...
Curing Methods01:26

Curing Methods

Concrete members with a small surface-to-volume ratio are cured by oiling and moistening the forms before casting the concrete member. These forms can be left in place for a prolonged period to prevent moisture loss, and can be wetted if made of a material suitable for wetting. If the forms are removed early, the concrete member is moistened and covered with polythene sheets to maintain moisture. For large horizontal concrete surfaces exposed to dry weather, a temporary covering is suspended...

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関連する実験動画

Updated: Jul 19, 2026

Synthesis of Hydrogels with Antifouling Properties As Membranes for Water Purification
07:32

Synthesis of Hydrogels with Antifouling Properties As Membranes for Water Purification

Published on: April 7, 2017

ハイドロゲルで封じ込められた脂質膜.

Tae-Joon Jeon1, Noah Malmstadt, Jacob J Schmidt

  • 1Department of Bioengineering, University of California-Los Angeles, Los Angeles, CA 90095, USA.

Journal of the American Chemical Society
|January 5, 2006
PubMed
まとめ

ポリマーヒドロゲル内の脂質膜を安定させ,安定した単一分子DNA分析を可能にしました. 封装された膜は,DNAの転位を100倍以上遅らせ,生物分子センサーアプリケーションを向上させました.

科学分野:

  • バイオフィジックス 生物物理学
  • マテリアルサイエンス 材料科学
  • ナノテクノロジー ナノテクノロジー

背景:

  • 平面性脂質膜は,膜タンパク質と生物分子相互作用の研究に不可欠です.
  • フリースタンドの膜は不安定で,単一分子の長期研究での応用が制限されています.
  • アルファ-ヘモリシン (aHL) チャンネルは,DNA分析のためのナノ孔感知に使用されます.

研究 の 目的:

  • ポリマーヒドロゲル封じ込みを用いた平面性脂質膜の安定化のための方法を開発する.
  • 膜の安定性に対する封じ込めの効果と単一分子測定のための適合性を調査する.
  • aHLチャネルを通じた単一鎖DNAの転位ダイナミクスにカプセル膜の影響を評価する.

主な方法:

  • In situ光ポリメリゼーションは,ポリマーヒドロゲルの内部に,フリースタンドの平面性脂質膜をカプセル化するために使用されました.
  • 封装された膜の安定性は,時間とともに評価されました.
  • 単一分子測定は,組み込まれたアルファ-ヘモリシンチャネルタンパク質を用いて行われました.
  • 封入膜とゲルフリー膜の両方でaHL経由で単一鎖DNAの転位が分析されました.

主要な成果:

さらに関連する動画

Self-Assembly of Hybrid Lipid Membranes Doped with Hydrophobic Organic Molecules at the Water/Air Interface
06:28

Self-Assembly of Hybrid Lipid Membranes Doped with Hydrophobic Organic Molecules at the Water/Air Interface

Published on: May 1, 2020

Accessible Silicone Chip-to-Membrane Sealing Procedure for Flexible, Reliable Bonding
06:10

Accessible Silicone Chip-to-Membrane Sealing Procedure for Flexible, Reliable Bonding

Published on: March 20, 2026

関連する実験動画

Last Updated: Jul 19, 2026

Synthesis of Hydrogels with Antifouling Properties As Membranes for Water Purification
07:32

Synthesis of Hydrogels with Antifouling Properties As Membranes for Water Purification

Published on: April 7, 2017

Self-Assembly of Hybrid Lipid Membranes Doped with Hydrophobic Organic Molecules at the Water/Air Interface
06:28

Self-Assembly of Hybrid Lipid Membranes Doped with Hydrophobic Organic Molecules at the Water/Air Interface

Published on: May 1, 2020

Accessible Silicone Chip-to-Membrane Sealing Procedure for Flexible, Reliable Bonding
06:10

Accessible Silicone Chip-to-Membrane Sealing Procedure for Flexible, Reliable Bonding

Published on: March 20, 2026

  • 封装された脂質膜は,少なくとも5日間の安定性を示しました.
  • ポリマーヒドロゲルは,組み込まれたaHLタンパク質の単分子測定のための安定した環境を提供しました.
  • 封じ込め膜におけるaHL経由の単一鎖DNA転位は,ゲルフリー膜と比較して100倍以上遅くなりました.
  • 安定した膜は,DNAの単分子分析の強化を容易にした.
  • 結論:

    • In situ光ポリメリゼーションは,ポリマーヒドロゲル内の平面性脂質膜を効果的に安定させます.
    • 封装された膜は,単一分子生物物理学的研究のための長期的な強力なプラットフォームを提供します.
    • DNA転位の有意な減速は,高度なDNA分析と生物分子センシングに影響を及ぼします.
    • この技術は,バイオ分子センサー,膜タンパク質研究,薬剤開発の応用に期待されています.