中年における体量指数と,高齢における入院と死亡率
Lijing L Yan1, Martha L Daviglus, Kiang Liu
1Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Ill 60611, USA. lijing@northwestern.edu
JAMA
|January 13, 2006
まとめ
中年の肥満は,他の危険因子のない人でも,高齢の心臓病や糖尿病による入院や死亡のリスクを大幅に高めます. 健康的な体重を維持することは,長期的な心血管の健康に不可欠です.
科学分野:
- 心臓病学 心臓病学
- 公衆衛生は公衆衛生である.
- エピデミオロジー エピデミオロジー
背景:
- 肥満は健康状態の悪化と関連しているが,心臓血管疾患への影響については依然として議論されている.
- 確立された危険因子には,高血圧とコレステロールレベルが含まれます.
研究 の 目的:
- 中年期のボディマス指数と後年期の罹病率と死亡率との関連を調べる.
- 他の主要な心血管疾患の危険因子があるか否かの個体において,この関係を評価する.
主な方法:
- シカゴ・ハート・アソシエーション・デテクション・プロジェクトから17,643人の成年者 (31歳から64歳) を対象とした前向きな研究.
- 参加者は,心血管リスク (低,中等,高) とボディマス指数 (正常,過体重,肥満) によって分類されました.
- 冠動脈性心疾患,心血管疾患,糖尿病による入院および死亡率の追跡調査は65歳から実施した.
主要な成果:
- 中年の肥満者は,すべてのリスクカテゴリーにおいて,正常体重の個人に比べて,冠動脈疾患による死亡と入院のリスクが高くなりました.
- この関連性は,心血管疾患でも観察され,特に糖尿病では顕著でした.
- 結果はシストリック血圧とコレステロールレベルに調整された.
結論:
- 中年の肥満は,高齢における悪質な心血管疾患および糖尿病関連のアウトカムのための独立したリスク因子です.
- 肥満の個人は,ベースラインの心血管リスク要因に関係なく,入院と死亡リスクの増加に直面しています.
- 中年期に正常な体重指数を維持することは,長期的な健康に不可欠です.
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