ヒップ骨折とフッ素化,ユタ州の高齢者集団における
C Danielson1, J L Lyon, M Egger
1Department of Family and Preventive Medicine, University of Utah, Salt Lake City 84132.
JAMA
|August 12, 1992
まとめ
この研究では,1ppmのフッ化水は,高齢の男性と女性の股関節骨折リスクのわずかな,しかし有意な増加と関連していることが判明しました. これらの発見は,低レベルのフッ化物曝露と高齢者の骨折発生率の増加との潜在的な関連を示唆しています.
科学分野:
- 公衆衛生は公衆衛生である.
- エピデミオロジー エピデミオロジー
- ゲロントロジーはゲロントロジーの学科です.
背景:
- 水のフッ素化は,歯の健康のための一般的な公衆衛生対策です.
- 骨の健康,特に高齢者の股関節骨折に対するフッ化水の影響については,さらなる調査が必要である.
研究 の 目的:
- コミュニティの水のフッ素化が百万分1 (ppm) で,65歳以上の人々の股関節骨折の発生率との関連を評価する.
主な方法:
- 生態系コホート研究デザインが採用されました.
- ユタ州の3つの地域における股関節骨折発生率の比較:フッ化水 (1ppm) を摂取した地域と,フッ化水を使用していない地域.
- 特定の症例を除いて,65歳以上の個人における7年間の初回の股関節骨折の退院データを分析した.
主要な成果:
- フッ素化地域に住む女性では,非フッ素化地域 (95%CI=1.08〜1.46) に比べて,骨骨折の相対リスクは1.27であった.
- 酸化地域に住む男性では,非酸化地域 (95%CI=1.00〜1.81) に比べて,酸性骨折の相対リスクは1.41であった.
結論:
- この研究では,コミュニティの水中のフッ素1ppmに曝露した男性と女性の両方で,統計的に有意な部骨折リスクの増加を特定しました.
- これらの発見は,水中のフッ化物への低レベルの曝露が,高齢者集団における部骨折のリスクの増加と関連している可能性があることを示唆しています.
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