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Updated: Jul 8, 2026

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells
09:04

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells

Published on: May 22, 2014

痛風に関連する尿酸結晶は,NALP3炎症ゾームを活性化させます

Fabio Martinon1, Virginie Pétrilli, Annick Mayor

  • 1Department of Biochemistry, University of Lausanne, Chemin des Boveresses 155, 1066 Epalinges, Switzerland.

Nature
|January 13, 2006
PubMed
まとめ

結晶の堆積は,NALP3炎症体を活性化させ,インタールイキン-1βおよびインタールイキン-18の産生につながり,痛風および偽痛風の炎症を引き起こします. この経路は,結晶誘発の炎症反応に不可欠です.

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