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Updated: Jul 15, 2026

Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine
09:14

Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine

Published on: February 16, 2018

設計されたアミノ酸によって触媒化された直接非対称なアンチマニッヒ型反応

Susumu Mitsumori1, Haile Zhang, Paul Ha-Yeon Cheong

  • 1The Skaggs Institute for Chemical Biology and the Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, USA.

Journal of the American Chemical Society
|January 26, 2006
PubMed
まとめ

新しい触媒である (3R,5R) -5-メチル-3-ピロリジンカルボキシル酸 (RR35) は,高度に選択的なアンチマニッヒ型反応を可能にします. この有機触媒は,低触媒負荷の温和な条件下で優れたステレオ制御とエナチオ選択性を達成します.

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