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Updated: Jul 16, 2026

Associated Chromosome Trap for Identifying Long-range DNA Interactions
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溶液中のヒトBCL-2プロモーター領域で形成される,並列/反並列G鎖を混合した内分子G四重複構造

Jixun Dai1, Thomas S Dexheimer, Ding Chen

  • 1College of Pharmacy, University of Arizona, Tucson, 85721, USA.

Journal of the American Chemical Society
|January 26, 2006
PubMed
まとめ

研究者らは,ヒトのbcl-2プロモーターで最初のG-四重複構造を発見した. 混合G鎖を持つこの新しい構造は,bcl-2遺伝子発現を調節する抗癌薬のための新しい標的を提供します.

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