B12依存メチルマロニル-CoAミュータゼにおける根幹生成のメカニズムに関する計算による洞察

Renata A Kwiecien1, Ilja V Khavrutskii, Djamaladdin G Musaev

  • 1Institute of Applied Radiation Chemistry, Technical University of Lodz, Poland.

まとめ

メチルマロニル-CoAミュータゼは,コバルト-炭素結合の割れ前に構成の変化を含む段階的なメカニズムを使用します. ラジカル形成に不可欠なこのプロセスは,重要なエネルギーと構造の詳細を明らかにするために計算モデル化されています.

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