関連する実験動画

Updated: Jul 16, 2026

Measuring DNA Damage and Repair in Mouse Splenocytes After Chronic In Vivo Exposure to Very Low Doses of Beta- and Gamma-Radiation
11:24

Measuring DNA Damage and Repair in Mouse Splenocytes After Chronic In Vivo Exposure to Very Low Doses of Beta- and Gamma-Radiation

Published on: July 3, 2015

REGgamma:破壊へのショートカット

Pengbo Zhou1

  • 1Department of Pathology and Laboratory Medicine, Weill Medical College and Graduate School of Medical Sciences of Cornell University, New York, NY 10021, USA. pez2001@med.cornell.edu

Cell
|January 28, 2006
PubMed
まとめ

細胞のタンパク質破壊には通常,ATPと26Sプロテアソームのユビキチネーションが必要です. この研究では,プロテアソーム活性化剤REGgammaが,20Sプロテアソームによるステロイド受容体共活性化剤SRC-3の分解を媒介し,ATPとユビキチンから独立していることが明らかになりました.

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