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Updated: May 13, 2026

Using RNA-mediated Interference Feeding Strategy to Screen for Genes Involved in Body Size Regulation in the Nematode C. elegans
11:22

Using RNA-mediated Interference Feeding Strategy to Screen for Genes Involved in Body Size Regulation in the Nematode C. elegans

Published on: February 13, 2013

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機能プロテオミクスは,C. elegans DCR-1の生化学的ニッチを,複数の小RNA媒介経路で明らかにしています

Thomas F Duchaine1, James A Wohlschlegel, Scott Kennedy

  • 1Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, 01605, USA.

Cell
|January 28, 2006
PubMed
まとめ

この研究では,C. elegans Dicer (DCR-1) がタンパク質と相互作用して,遺伝子サイレンスに不可欠な小さなRNAを生成する方法が明らかにされています. これらの発見は,Dicer媒介経路の複雑な相互作用を明らかにしています.

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CRISPR and crRNAs02:53

CRISPR and crRNAs

Bacteria and archaea are susceptible to viral infections just like eukaryotes; therefore, they have developed a unique adaptive immune system to protect themselves. Clustered regularly interspaced short palindromic repeats and CRISPR-associated proteins (CRISPR-Cas) are present in more than 45% of known bacteria and 90% of known archaea.
The CRISPR-Cas system stores a copy of foreign DNA in the host genome and uses it to identify the foreign DNA upon reinfection. CRISPR-Cas has three different...