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Updated: Jul 29, 2026

Co-immunoprecipitation Assay for Studying Functional Interactions Between Receptors and Enzymes
09:40

Co-immunoprecipitation Assay for Studying Functional Interactions Between Receptors and Enzymes

Published on: September 28, 2018

フォスフォタンパク質とタンパク質の表面相互作用を2点相互作用を通じてZn (II) ディピコライアミンベースの人工受容体を使用して効果的に破壊する

Akio Ojida1, Masa-aki Inoue, Yasuko Mito-oka

  • 1Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Kyoto, 615-8510, Japan.

Journal of the American Chemical Society
|February 9, 2006
PubMed
まとめ

研究者らは,二酸化リン酸化ペプチドを結合する小分子を開発し,フォスフォタンパク質-タンパク質の相互作用を妨害しました. この新しい戦略は,タンパク質シグナル伝達経路のターゲットを絞った阻害剤の作成に有望であることが示されています.

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