エプスタイン・バーウイルス潜伏膜タンパク質1によるbcl-2発現誘導は,感染したB細胞をプログラム細胞死から保護する

S Henderson1, M Rowe, C Gregory

  • 1Department of Cancer Studies University of Birmingham, England.

Cell
|June 28, 1991
PubMed
まとめ

エプスタイン・バーウイルス (EBV) 潜伏膜タンパク質1 (LMP 1) は,細胞腫瘍遺伝子bcl-2を上位に調節することによって,B細胞をアポトーシスから保護する. この発見は,EBVの持続性と関連する癌を理解するために極めて重要です.

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