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ビタミンDを介したヒトの抗微生物反応のトール型受容体の誘発

Philip T Liu1, Steffen Stenger, Huiying Li

  • 1Department of Microbiology, Immunology, and Molecular Genetics, University of California at Los Angeles, Los Angeles, CA 90095, USA.

Science (New York, N.Y.)
|February 25, 2006
PubMed
まとめ

人間のマクロファージにおけるトール型受容体 (TLR) の活性化により,ビタミンDが増加し,Mycobacterium tuberculosisと戦うために抗菌性ペプチドであるキャセリシジンが強化されます. 特定の集団におけるビタミンD濃度の低下は,結核の感受性の増加と相関しています.

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