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Updated: Jun 25, 2026

A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α
11:27

A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α

Published on: November 2, 2018

遺伝子毒性刺激に対する反応として,キナーゼATMとNF-kappaBのシグナル伝達との分子結合

Zhao-Hui Wu1, Yuling Shi, Randal S Tibbetts

  • 1Department of Pharmacology, University of Wisconsin-Madison, 301 SMI, 1300 University Avenue, Madison, WI 53706, USA.

Science (New York, N.Y.)
|February 25, 2006
PubMed
まとめ

NF-kappaBエッセンシャルモジュレーター (NEMO) タンパク質は,ATMとIKKの信号伝達経路をリンクしています. この相互作用は,DNA損傷に対する反応としてNF-kappaBを活性化し,細胞死経路に影響を与えます.

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NF-κB-dependent Luciferase Activation and Quantification of Gene Expression in Salmonella Infected Tissue Culture Cells10:57

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