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Updated: Jul 17, 2026

Biochemical and Structural Characterization of the Carbohydrate Transport Substrate-binding-protein SP0092
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Published on: October 2, 2017

病変を探すDNAグリコシラーゼの構造

Anirban Banerjee1, Webster L Santos, Gregory L Verdine

  • 1Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.

Science (New York, N.Y.)
|February 25, 2006
PubMed
まとめ

MutMのようなDNAグリコシラゼは,プローブ残留物と曲塩基対を挿入することによって,無傷のDNAを積極的に探求する. このメカニズムは,損傷したDNA核塩基を効率的に特定し,除去することを可能にします.

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Proteins are one of the most abundant organic molecules in living systems and have the most diverse range of functions of all macromolecules. Proteins may be structural, regulatory, contractile, or protective. They may serve in transport, storage, or membranes; or they may be toxins or enzymes. Their structures, like their functions, vary greatly. They are all, however, amino acid polymers arranged in a linear sequence.
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