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Updated: Jul 18, 2026

Profiling of Methyltransferases and Other S-adenosyl-L-homocysteine-binding Proteins by Capture Compound Mass Spectrometry (CCMS)
17:12

Profiling of Methyltransferases and Other S-adenosyl-L-homocysteine-binding Proteins by Capture Compound Mass Spectrometry (CCMS)

Published on: December 20, 2010

S-アデノシル-L-メチオニンの非自然なコファクターアナログを使用した天然製品の多様化

Changsheng Zhang1, Rachel L Weller, Jon S Thorson

  • 1Laboratory for Biosynthetic Chemistry, University of Wisconsin National Cooperative Drug Discovery Group, Pharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison, 777 Highland Avenue, Madison, WI 53705-2222, USA.

Journal of the American Chemical Society
|March 2, 2006
PubMed
まとめ

研究者らは,メチルトランスフェラーゼのための新しい合成コファクターを開発し,さまざまな薬物のような分子の作成を可能にしました. このブレークスルーは,非自然なコファクターを利用することで,薬物発見における天然製品酵素の使用を拡大します.

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Sequence-specific Labeling of Nucleic Acids and Proteins with Methyltransferases and Cofactor Analogues12:07

Sequence-specific Labeling of Nucleic Acids and Proteins with Methyltransferases and Cofactor Analogues

Published on: November 22, 2014

In Vitro Assay to Measure Phosphatidylethanolamine Methyltransferase Activity09:33

In Vitro Assay to Measure Phosphatidylethanolamine Methyltransferase Activity

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Cofactors and Coenzymes

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Phase II Reactions: Methylation Reactions

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