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Updated: Jul 22, 2026

Detection of Functional Matrix Metalloproteinases by Zymography
09:30

Detection of Functional Matrix Metalloproteinases by Zymography

Published on: November 8, 2010

古いリガンドの新たな役割:亜鉛金属タンパク質アゼのチェレータを識別する

Faith E Jacobsen1, Jana A Lewis, Seth M Cohen

  • 1Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California 92093, USA.

Journal of the American Chemical Society
|March 9, 2006
PubMed
まとめ

研究者らは,マトリックス金属タンパク質酵素 (MMP) の強力な非ヒドロキサート抑制剤である新しい亜鉛結合群 (ZBG) を開発した. これらの新しいMMP阻害剤は,伝統的な化合物と比較して有意に改善された効能を示し,選択的な金属酵素阻害を提供します.

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