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Updated: Aug 9, 2026

Analysis of Translation Initiation During Stress Conditions by Polysome Profiling
10:59

Analysis of Translation Initiation During Stress Conditions by Polysome Profiling

Published on: May 19, 2014

細胞mRNAの5'リーダーによって媒介される翻訳の内部開始

D G Macejak1, P Sarnow

  • 1Department of Biochemistry, Biophysics and Genetics, University of Colorado Health Sciences Center, Denver 80262.

Nature
|September 5, 1991
PubMed
まとめ

ユカリオットのメッセンジャーRNAは,5'キャップ構造だけでなく,内部リボソーム結合を使用して翻訳を開始することができます. このメカニズムは,キャップ依存経路が遮断されたときに,ウイルス感染中に細胞のmRNA翻訳を可能にします.

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Toeprinting Analysis of Translation Initiation Complex Formation on Mammalian mRNAs

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