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Updated: May 4, 2026

Molecular Analysis of Endothelial-mesenchymal Transition Induced by Transforming Growth Factor-β Signaling
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Published on: August 3, 2018

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エミリン1は,TGF-βの成熟を血圧ホメオスタシスと結びつける

Luca Zacchigna1, Carmine Vecchione, Antonella Notte

  • 1Developmental Signaling Laboratory, Department of Histology Microbiology and Medical Biotechnologies, University of Padua, viale Colombo 3, 35121 Padua, Italy.

Cell
|March 15, 2006
PubMed
まとめ

エミリン1欠乏症は,変形成長因子-β (TGF-β) 信号伝達を強化することによって血圧を上昇させます. TGF-β1レベルを回復すると,Emilin1ノックアウトマウスの血圧が正常化し,TGF-β調節が明らかになる.

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