RNAi,

Charlotte Grimaud1, Frédéric Bantignies, Manika Pal-Bhadra

  • 1Institute of Human Genetics, CNRS, 141 rue de la Cardonille, 34396 Montpellier Cedex 5, France.

Cell
|March 15, 2006
PubMed
まとめ

Dicer-2,PIWI,およびArgonaute1を含むRNA干渉 (RNAi) 機構は,ポリコンブ群 (PcG) のタンパク質媒介遺伝子サイレンシングに不可欠である. RNAiコンポーネントは,PcG標的遺伝子の調節に不可欠な長距離DNA接触を維持しています.

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