妊娠中の急性心筋梗塞:米国の人口ベースの研究
Andra H James1, Margaret G Jamison, Mimi S Biswas
1Division of Maternal-Fetal Medicine, Duke University Medical Center, Durham, NC 27710, USA. andra.james@duke.edu
Circulation
|March 15, 2006
まとめ
妊娠に関連した急性心筋梗塞はまれですが,特に高齢の女性にとって重大なリスクがあります. 主な危険因子には,高血圧,血栓性,糖尿病,喫煙,母親の高齢化などが含まれる.
科学分野:
- 心血管医学 心血管医学
- 産科・婦人科 産科・婦人科
- 公衆衛生は公衆衛生である.
背景:
- 妊娠中の急性心筋梗塞 (AMI) は,まれだが深刻な合併症である.
- 発症率,死亡率,およびリスク要因を理解することは,母親の健康にとって極めて重要です.
- 妊娠は,AMIのリスクが3〜4倍に増加するリスクと関連しています.
研究 の 目的:
- 妊娠に関連した急性心筋梗塞の発生率,死亡率,およびリスク要因を米国で決定する.
- 妊娠中にAMIリスクを高める特定の疾患および産科合併症を特定する.
主な方法:
- 2000年から2002年まで全国の入院患者サンプル (NIS) データベースを利用した.
- 急性心筋梗塞の診断で,妊娠に関連した放出を分析した.
- 重要なリスク要因を特定するために多変数ロジスティック回帰を使用しました.
主要な成果:
- 妊娠に関連したAMIの発生率は10万出産当たり6.2であり,死亡率は5.1%であった.
- 重要な危険因子には,高血圧,血栓性,糖尿病,喫煙,輸血,産後感染症,および30歳以上の年齢が含まれています.
- 40歳以上の女性は,20歳未満の女性と比較して,AMIの発症率が30倍高かった.
結論:
- 妊娠に関連したAMIはまれですが,かなりのリスクを伴います.
- 高血圧,糖尿病,喫煙などの修正可能な危険因子は,AMIの確率を大幅に高めます.
- これらのリスク要因をターゲットにすることで,妊娠に関連した心筋梗塞の発生率を潜在的に減らすことができます.
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