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Updated: Jul 28, 2026

Iterative Optimization of DNA Duplexes for Crystallization of SeqA-DNA Complexes
11:42

Iterative Optimization of DNA Duplexes for Crystallization of SeqA-DNA Complexes

Published on: November 1, 2012

CAP-DNA複合体の結晶構造:DNAは90度曲がっている

S C Schultz1, G C Shields, T A Steitz

  • 1Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511.

Science (New York, N.Y.)
|August 30, 1991
PubMed
まとめ

結晶構造は,Escherichia coliのカタボライト遺伝子アクティベータータンパク質 (CAP) が特定の塩基対のキンクを通してDNAを90度曲げることを明らかにしています. このDNA曲折とタンパク質-DNA相互作用は,転写活性化の鍵です.

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