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Updated: Jun 10, 2026

Preparation of Oligomeric β-amyloid1-42 and Induction of Synaptic Plasticity Impairment on Hippocampal Slices
04:41

Preparation of Oligomeric β-amyloid1-42 and Induction of Synaptic Plasticity Impairment on Hippocampal Slices

Published on: July 15, 2010

脳内の特定のアミロイドベータタンパク質組成は,記憶を損なう

Sylvain Lesné1, Ming Teng Koh, Linda Kotilinek

  • 1Department of Neurology, University of Minnesota Medical School, Minneapolis, Minnesota 55455, USA.

Nature
|March 17, 2006
PubMed
まとめ

溶解性アミロイドベータ集合体であるAbeta*56は,プラークが形成される前に老齢マウスの記憶喪失を引き起こします. この発見は,アベタ*56がアルツハイマー病における認知機能低下の早期の原動力である可能性があることを示唆しています.

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