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SV2はボトルニウム神経毒素Aのタンパク質受容体です

Min Dong1, Felix Yeh, William H Tepp

  • 1Howard Hughes Medical Institute and Department of Physiology, University of Wisconsin, Madison, WI 53706, USA.

Science (New York, N.Y.)
|March 18, 2006
PubMed
まとめ

ボトリヌム神経毒素A (BoNT/A) は,シナプス核膜タンパク質2 (SV2) と結合してニューロンに侵入する. この発見により,SV2は,神経細胞へのBoNT/Aの侵入に不可欠なタンパク質受容体であることを明らかにした.

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