関連する実験動画

Updated: Jul 12, 2026

In Situ Detection of Ribonucleoprotein Complex Assembly in the C. elegans Germline using Proximity Ligation Assay
08:56

In Situ Detection of Ribonucleoprotein Complex Assembly in the C. elegans Germline using Proximity Ligation Assay

Published on: May 5, 2020

プロリルイソメラーゼPin1は,アミロイド前駆タンパク質の加工とアミロイドベータの生産を調節する

Lucia Pastorino1, Anyang Sun, Pei-Jung Lu

  • 1Cancer Biology Program, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA.

Nature
|March 24, 2006
PubMed
まとめ

Pin1プロリルイソメラーゼは,アミロイド前駆タンパク質 (APP) の加工とアミロイドベータ (Abeta) の生産を調節する. Pin1の緩和は,毒性の高いAbeta42を増加させ,アルツハイマー病におけるtauとAbetaの病理を結びつける.

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Isolation and Differentiation of Primary White and Brown Preadipocytes from Newborn Mice09:00

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