関連する実験動画

Updated: Jul 9, 2026

RNAi Mediated Gene Knockdown and Transgenesis by Microinjection in the Necromenic Nematode Pristionchus pacificus
06:57

RNAi Mediated Gene Knockdown and Transgenesis by Microinjection in the Necromenic Nematode Pristionchus pacificus

Published on: October 16, 2011

非ヒトの霊長類におけるRNAi媒介による遺伝子サイレンシング

Tracy S Zimmermann1, Amy C H Lee, Akin Akinc

  • 1Alnylam Pharmaceuticals Inc., 300 Third Street, Cambridge, Massachusetts 02142, USA. tzimmermann@alnylam.com

Nature
|March 28, 2006
PubMed
まとめ

リポソームに小型の干渉RNA (siRNA) を系統的に送り込むことは,ヒト以外の霊長類におけるアポリポプロテインB (ApoB) を効果的に静止させました. このRNA干渉療法では,強力で持続的な遺伝子静止と低コレステロールレベルが示され,その治療的可能性を裏付けました.

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Rearing and Double-stranded RNA-mediated Gene Knockdown in the Hide Beetle, Dermestes maculatus09:57

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