関連する実験動画

Updated: Jul 24, 2026

Mouse Naïve CD4+ T Cell Isolation and In vitro Differentiation into T Cell Subsets
07:12

Mouse Naïve CD4+ T Cell Isolation and In vitro Differentiation into T Cell Subsets

Published on: April 16, 2015

T細胞の活性化において,先天的な免疫シグナル伝達分子IRAK-4が果たす重要な役割

Nobutaka Suzuki1, Shinobu Suzuki, Douglas G Millar

  • 1Laboratory for Cell Signaling, RIKEN Research Center for Allergy and Immunology, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa 230-0045, Japan.

Science (New York, N.Y.)
|April 1, 2006
PubMed
まとめ

インタールイキン-1受容体関連キナーゼ4 (IRAK-4) は,先天性免疫だけでなく,適応性免疫に不可欠です. その欠如は,T細胞活性化に不可欠な信号伝達経路を妨害することによって,T細胞の反応を損なう.

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