関連する実験動画

Updated: Jul 15, 2026

Demonstration of Proteolytic Activation of the Epithelial Sodium Channel (ENaC) by Combining Current Measurements with Detection of Cleavage Fragments
08:56

Demonstration of Proteolytic Activation of the Epithelial Sodium Channel (ENaC) by Combining Current Measurements with Detection of Cleavage Fragments

Published on: July 5, 2014

Na+チャネル内のリン酸化部位は,タンパク質キナーゼCによる調節に必要なものです

J W West1, R Numann, B J Murphy

  • 1Department of Pharmacology, University of Washington, Seattle 98195.

Science (New York, N.Y.)
|November 8, 1991
PubMed
まとめ

タンパク質キナーゼCの活性化は,セリン1506.6をリン酸化することによって,電圧ゲートされたナトリウムチャネルを調節する. このリン酸化部位は,ナトリウムチャネル活性と刺激性細胞におけるアクションポテンシャル生成の調節に極めて重要です.

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