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Updated: Aug 9, 2026

A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species
08:12

A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species

Published on: August 16, 2018

Me2Znの高度なエナチオセレクティブ添加は,ClCr (((サレン)) によって触媒化されたアルデヒドに添加されます

Pier Giorgio Cozzi1, Peter Kotrusz

  • 1Dipartimento di Chimica, University of Bologna, G. Ciamician, via Selmi 2, 40126 Bologna, Italy. piergiorgio.cozzi@unibo.it

Journal of the American Chemical Society
|April 13, 2006
PubMed
まとめ

この研究では,アルデヒドにダイエチル亜鉛 (Me2Zn) を添加するための新しいエナンチオセレクティブプロセスを導入しています. この方法は,ClCr(Salenによって触媒化され,穏やかな条件下で高いエナティオメール過剰 (71-99%) を達成します.

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