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Updated: Jul 15, 2026

Atomic Scale Structural Studies of Macromolecular Assemblies by Solid-state Nuclear Magnetic Resonance Spectroscopy
14:55

Atomic Scale Structural Studies of Macromolecular Assemblies by Solid-state Nuclear Magnetic Resonance Spectroscopy

Published on: September 17, 2017

圧力依存型NMRリラクゼーション分散によるタンパク質折りたたみ反応の移行状態アンサンブルを検知する

Dmitry M Korzhnev1, Irina Bezsonova, Ferenc Evanics

  • 1Department of Medical Genetics, University of Toronto, Toronto, Ontario, Canada, M5S 1A8.

Journal of the American Chemical Society
|April 13, 2006
PubMed
まとめ

この研究は,タンパク質の折りたたみにおける移行状態アンサンブル (TSE) が崩壊し,緩やかに詰め込まれ,水分化されていることを明らかにしています. 速度制限のステップの後,水放出が発生し,折り畳み障壁に影響を与えます.

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